Copa Sul-Americana 2022Third Phase - Round of 16 - 1st Leg | ||
| 2 - 1 | 
|
| Independiente del Valle [ECU] | Lanús [ARG] | |
| Club Social y Deportivo Independiente | Club Atlético Lanús | |
| Venue | Banco de Guayaquil, Quito, Ecuador (Estadio Banco de Guayaquil) |
| Date | 06/30/2022 - Thursday |
 Video | |
| Goals |
 Independiente del Valle [ECU] |
| Schunke 45+1, Ayovi 90+3 |
 Lanús [ARG] |
| Belmonte 60 |
| Lineups | ||||
| Independiente del Valle [ECU]
| ||||
 | Schunke | 45+1 | ||
| | Ayovi | 90+3 | ||
| Lanús [ARG]
| ||||
| | Belmonte | 60 | ||
