Copa Sul-Americana 2022First Phase - 2nd Leg | ||
| 0 - 1 | 
|
| Antofagasta [CHI] | Unión Española [CHI] | |
| Club de Deportes Antofagasta S.A.D.P. | Club Unión Española S.A.D.P. | |
| Venue | Regional de Antofagasta, Antofagasta, Chile (Estádio Regional de Antofagasta) |
| Date | 03/17/2022 - Thursday |
| Time | 19:15 [UTC-3] |
 Video | |
| Goals |
 Unión Española [CHI] |
| Pineiro 50 |
| Lineups | ||||
| Unión Española [CHI]
| ||||
 | Pineiro | 50 | ||
| Observations |
| Antofagasta [CHI] qualified |
| Scouts | |||
| Category | Antofagasta [CHI] | Unión Española [CHI] | |
 Missed penalties | 0 | 1 | |
